Mitochondria & Energy Metabolism

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Research interests

Mitochondrial plasticity
Mitochondrial gene expression
Nucleotide metabolism

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New article in Nature Metabolism
May 2023
Our story on uridine catabolism for energy production is out in Nature Metabolism! Spearheaded by co-first authors Owen Skinner (MGH/Harvard) and Joan Blanco-Fernandez (from the lab), with Vamsi Mootha and many collaborators. PDF
Introducing Dead-Seq for synthetic lethal screening
May 2023
In a new manuscript by Joan Blanco-Fernandez we introduce Dead-Seq, a powerful experimental method for converting negative- into positive-selection screens, compatible with CRISPR screening, ORFeome screening and more. PDF